Ok, here's my take and slight novel. I married a pretty insensitive guy who really tried hard at "doing the right thing" when it came to holidays...lol. So hopefully my suggestions will help you
You know, I think it's great you are asking us, a bunch of chicks, our opinion about what you should do for YOUR lady, but it's your
My meaning: you would know if she likes to be wine & fine-dined at a quiet dinner, or if she prefers to just stay in, or if she would think it's endearing to get "honey-do coupons," or a maid-service for a few months (like Molly Maid or Merry Maids), or if the ideal gift would just be a Swedish massage and mani/pedi... you know what I mean? We don't know your lovely wife - we are all suggesting things that we would like - but you know the saying "someone's trash is another [wo]man's treasure."
You said she has the following likes/wants:
And given your timeframe of roughly 2 days.... #1: A card would be nice! I would say, you would have to get on the ball quick to get something. Since she is a nurse, and needing some serious R+R, I think you are on the right track! (I work as a recruiter for a health system hiring nurses!) A gift certificate is not insensitive from Sephora or a day spa. Then she can choose what she wants - especially if the day spa has options of packages like adding hot stone therapy or paraffin wax. Just remember - these places will be most likedly BOOKED up for the weekend. You might be able to get a mani/pedi for her though at an independent Nail Salon (you know, the Asian ones - my people will hook her up! hehe j/k! I kid, I kid! You ever seen comedian Angela Johnson? hilarious!)
I know women are very particular in what brands/lines they use and color they use if you go and buy her makeup and body products - unless it's something you are replacing for her or wanting to suggest something for her to try because you "fancy" it (for instance - as a guy you would replace your fave deodorant or toothpaste, we do the same with our fave lipsticks, eyeliner/mascaras, body lotion, body washes, etc.)
Anyhoo, you are awesome for just trying to make her happy on this day...it's a "Hallmark Holiday"... it's the thought that counts. You totally get an A+++++ for effort!